Focal Segmental Glomerulosclerosis – Does Treatment Work?
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چکیده
منابع مشابه
Focal segmental glomerulosclerosis--does treatment work?
This study also confirms that the mean time to remission in treated FSGS patients can be as long as 5 months and that treatment should continue beyond that time. It reports a relapse rate of 20% and a spontaneous remission rate of 30.7%. Recent studies have also demonstrated higher spontaneous remission rates than those previously [7] , particularly in comparison with American series. The highe...
متن کاملFocal Segmental Glomerulosclerosis.
Focal segmental glomerulosclerosis (FSGS) is a leading cause of kidney disease worldwide. The presumed etiology of primary FSGS is a plasma factor with responsiveness to immunosuppressive therapy and a risk of recurrence after kidney transplant-important disease characteristics. In contrast, adaptive FSGS is associated with excessive nephron workload due to increased body size, reduced nephron ...
متن کاملIdiopathic focal segmental glomerulosclerosis.
Idiopathic focal segmental glomerulosclerosis (FSGS) is a primary glomerular disease that essentially represents a form of chronic, progressive renal fibrosis for which there is no discernible cause. Often presenting with or eventually manifesting the nephrotic syndrome, this disease is increasing in incidence in both children and adults. Therapy continues to be a challenge, although some patie...
متن کاملCollapsing Focal Segmental Glomerulosclerosis
Background and objectives: Treatment with IFN is rarely associated with nephrotic syndrome and renal biopsy findings of minimal-change disease or FSGS. Design, setting, participants, & measurements: We report 11 cases of collapsing FSGS that developed during treatment with IFN and improved after discontinuation of therapy. Results: The cohort consists of seven women and four men with a mean age...
متن کاملUnwinding focal segmental glomerulosclerosis
Focal segmental glomerulosclerosis (FSGS) represents the most common primary glomerular disease responsible for the development of end-stage renal disease (ESRD) in the United States (US). The disease progresses from podocyte injury to chronic kidney disease (CKD), ultimately leading to total nephron degeneration. Extensive basic science research has been conducted to unwind the mechanisms of F...
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ژورنال
عنوان ژورنال: Nephron Clinical Practice
سال: 2006
ISSN: 1660-2110
DOI: 10.1159/000093994